1062 PROTECTION BY SERUM ANTIBODIES IN EXPERIMENTAL NONTYPABLE HAEMOPHILUS INFLUENZAE (NTHI) OTITIS MEDIA (OM)
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چکیده
منابع مشابه
Title: Pneumococcal phenotype and interaction with nontypeable Haemophilus influenzae as determinants of otitis media progression Running title: Otitis media progression by S. pneumoniae and NTHi
Background: Mixed-species otitis media caused by Streptococcus pneumoniae (Spn) and nontypeable Haemophilus influenzae (NTHi) is associated with complex manifestations that are less common in pneumococcal infections without NTHi. We analyzed the microbiological composition of middle ear fluid (MEF) cultures and nasopharyngeal samples obtained before PCV7/13 rollout to identify bacterial factors...
متن کاملNon typable-Haemophilus influenzae biofilm formation and acute otitis media
BACKGROUND Non-typable Haemophilus influenzae (NT-Hi) infection is frequently associated with acute otitis media (AOM) treatment failure, recurrence or chronic otitis media. Persistence of otopathogens in a biofilm-structured community was implicated in these situations. Here, we compared biofilm production by H. influenzae strains obtained by culture of middle ear fluid (MEF) from children wit...
متن کاملModified Lipooligosaccharide Structure Protects Nontypeable Haemophilus influenzae from IgM-Mediated Complement Killing in Experimental Otitis Media
UNLABELLED Nontypeable Haemophilus influenzae (NTHi) is a Gram-negative, human-restricted pathogen. Although this bacterium typically colonizes the nasopharynx in the absence of clinical symptoms, it is also one of the major pathogens causing otitis media (OM) in children. Complement represents an important aspect of the host defense against NTHi. In general, NTHi is efficiently killed by compl...
متن کاملCorrection: Relationships between Mucosal Antibodies, Non-Typeable Haemophilus influenzae (NTHi) Infection and Airway Inflammation in COPD
[This corrects the article DOI: 10.1371/journal.pone.0167250.].
متن کاملCharacterization of antigens from nontypable Haemophilus influenzae recognized by human bactericidal antibodies. Role of Haemophilus outer membrane proteins.
Major outer membrane antigens, proteins, and lipopolysaccharides (LPSs), from nontypable Haemophilus influenzae were characterized and examined as targets for complement-dependent human bactericidal antibodies. Outer membranes from two nontypable H. influenzae isolates that caused otitis media and pneumonia (middle ear and transtracheal aspirates) were prepared by shearing organisms in EDTA. Th...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1985
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-198504000-01092